info:eu-repo/semantics/article
Reply to "comment on 'Free-Radical Formation by the Peroxidase-Like Catalytic Activity of MFe2O4 (M = Fe, Ni, and Mn) Nanoparticles'"
Fecha
2019-11Registro en:
Moreno Maldonado, Ana Carolina; Winkler, Elin Lilian; Raineri Andersen, Mariana; Toro Cordova, Alfonso; Rodriguez, Luis Miguel; et al.; Reply to "comment on 'Free-Radical Formation by the Peroxidase-Like Catalytic Activity of MFe2O4 (M = Fe, Ni, and Mn) Nanoparticles'"; American Chemical Society; Journal of Physical Chemistry C; 123; 46; 11-2019; 28511-28512
1932-7447
1932-7455
CONICET Digital
CONICET
Autor
Moreno Maldonado, Ana Carolina
Winkler, Elin Lilian
Raineri Andersen, Mariana
Toro Cordova, Alfonso
Rodriguez, Luis Miguel
Troiani, Horacio Esteban
Mojica Pisciotti, Mary Luz
Vasquez Mansilla, Marcelo
Tobia, Dina
Nadal, Marcela
Torres Molina, Teobaldo Enrique
de Biasi, Emilio
Ramos, Carlos Alberto
Goya, Gerardo Fabian
Zysler, Roberto Daniel
Lima, Enio Junior
Resumen
Recently we have reported a qualitative, quantitative and reproducible study of the generation of free radicals as a result of the surface catalytic activity of Fe3O4, Fe2O3, MnFe2O4 and NiFe2O4 nanoparticles as a function of the Fe2+/Fe3+ oxidation state under different pHs (4.8 and 7.4) and temperatures (25 ºC and 40 ºC) condition. These results were contrasted with those obtained from the in vitro experiments in BV2 cells incubated with dextran-coated magneticnanoparticles. Based on these results we affirm that our ferrite magnetic nanoparticles catalyze the formation of free radicals and the decomposition of H2O2 by a ?peroxidase-like? activity. In a comment on this article, Meunier and A. Robert question two points: First they assert that the measured free radicals are not produced by a peroxidase reaction. Also, based on a different normalization method from those reported in our work, they also discuss that the reaction is not catalytic. Here we reply the arguments of the authors about these two points.