info:eu-repo/semantics/article
Anti-Pathogenic Activity of Herbs Used in Argentinean Traditional Infusion
Fecha
2017-12Registro en:
Brodkiewicz, Ivana Yanina; Molina, Rocío Daniela Inés; Vega López, Guillermo Alfredo; Alberto, Maria Rosa; Vera, Nancy Roxana; et al.; Anti-Pathogenic Activity of Herbs Used in Argentinean Traditional Infusion; Avanti; Global Journal of Agricultural Innovation, Research & Development; 4; 12-2017; 36-46
2409-9813
CONICET Digital
CONICET
Autor
Brodkiewicz, Ivana Yanina
Molina, Rocío Daniela Inés
Vega López, Guillermo Alfredo
Alberto, Maria Rosa
Vera, Nancy Roxana
Arena, Mario Eduardo
Resumen
The anti-pathogenic activity of Acantholippia deserticola, Haplopappus baylahuen, Lippia integrifolia and Satureja parvifolia herbs used as traditional infusion were investigated. The extracts obtained were compared with respect to chromatographic profiles and antimicrobial activities. The dichloromethane and methanol extracts of the four herbs showed significant inhibition of Staphylococcus aureus and Pseudomonas aeruginosa growth and biofilm formation. The dichloromethane extract of Lippia integrifolia that showed the highest inhibitory effect on P. aeruginosa biofilm formation, was fractionated by column chromatography using a gradient of polarity, and the activities of the fractions were evaluated. In general, the lower polar fractions inhibited biofilm in correlation with bacterial growth. However, in more polar fractions the biofilm diminution is well correlated with the inhibition of AI production more than the bacterial development. The results provide scientific support to the usage of these herbs for the protection against foodborne diseases through different mode of actions. This effect is notably in L. integrifolia due that the fractions showed superior growth, biofilm and autoinducer inhibitory activity compared to crude extract.