info:eu-repo/semantics/article
Anti-adhesion and antibacterial activity of silver nanoparticles and graphene oxide-silver nanoparticle composites
Fecha
2020-07Registro en:
Gómez de Saravia, Sandra Gabriela; Rastelli, Silvia Elena; Angulo Pineda, Carolina; Palza, Humberto; Viera, Marisa Rosana; Anti-adhesion and antibacterial activity of silver nanoparticles and graphene oxide-silver nanoparticle composites; Universidade Federal do Rio de Janeiro; Matéria; 25; 2; 7-2020; 1-9
1517-7076
CONICET Digital
CONICET
Autor
Gómez de Saravia, Sandra Gabriela
Rastelli, Silvia Elena
Angulo Pineda, Carolina
Palza, Humberto
Viera, Marisa Rosana
Resumen
The rise of nanotechnology has allowed the development of several inorganic nanoparticles with strong biocidal properties against bacteria, fungi, and viruses. Among them, silver nanoparticles (AgNPs) stand out as one of the most promising antimicrobial nanomaterials. Graphene oxide (GO) is another attractive nanomaterial with antimicrobial properties. Although the antimicrobial effect of AgNPs and GO is known, the development of hybrid materials of GO-AgNPs has considerable interest in various ap-plications since they may exhibit synergistic bactericidal properties that exceed the yields of the individu-al components. The aims of this work were to evaluate the antimicrobial activity and anti-adhesion properties of AgNPs and GO-AgNPs nanocomposites for potential applications in antimicrobial coatings. The antimicrobial activity was tested by agar diffusion method. It was found that activity varied accord-ing to the synthesis procedure of the nanomaterials. Pseudomonas aeruginosa, Bacillus cereus and Ko-kuria rhizophila were the most susceptible strains. The nanocomposite GO- AgNPs synthetized using the ex-situ method exhibited the highest antibacterial activity against all the assayed strains. Similar results were obtained for bacterial adhesion inhibition tests. Thus, GO-AgNPs nanohybrids could be applied as antibacterial coatings to prevent bacterial biofilm development.