info:eu-repo/semantics/article
Larrea divaricata Cav (Jarilla): Production of superoxide anion, hydrogen peroxide and expression of zymosan receptors
Fecha
2008-09Registro en:
Davicino, Roberto Carlos; Martinez, Carolina; Mattar Domínguez, María Aída; Casali, Judith Yolanda; Correa, Silvia Graciela; et al.; Larrea divaricata Cav (Jarilla): Production of superoxide anion, hydrogen peroxide and expression of zymosan receptors; Taylor & Francis; Immunopharmacology And Immunotoxicology; 30; 3; 9-2008; 489-501
0892-3973
CONICET Digital
CONICET
Autor
Davicino, Roberto Carlos
Martinez, Carolina
Mattar Domínguez, María Aída
Casali, Judith Yolanda
Correa, Silvia Graciela
Aragón, Leslie Mary
Saidman, Elbio Antonio
Messina, Germán Alejandro
Micalizzi, Blas
Resumen
Larrea divaricata is a plant widely used in folk medicine in Argentina. This work aimed to study the mechanisms of decoction activity on the release of oxygen reactive species. Decoction increased the binding of zymosan-FITC and superoxide production. Cadmium decreased the superoxide production as well as malonate and barbital. Decoction decreased the release of hydrogen peroxide. Decoction increased the reduction of MTT but not when malonate and barbital were included. Together, decoction increased the expression of dectin-1 leading to increased superoxide production. It is possible that decoction increases the activity of peroxidase, and decreases the Cu, Zn-superoxide dismutase.