info:eu-repo/semantics/article
Nephrocalcinosis and proximal tubulopathy in Sjögren's Syndrome
Fecha
2018-06Registro en:
Baenas, Diego Federico; Flores Balverdi, Janet; Retamozo, Maria Soledad; Riscanevo, Nadia; Alvarez, Cecilia Susana; et al.; Nephrocalcinosis and proximal tubulopathy in Sjögren's Syndrome; Universidad Nacional de Córdoba; Revista de la Facultad de Ciencias Médicas; 75; 2; 6-2018; 138-142
0014-6722
1853-0605
CONICET Digital
CONICET
Autor
Baenas, Diego Federico
Flores Balverdi, Janet
Retamozo, Maria Soledad
Riscanevo, Nadia
Alvarez, Cecilia Susana
De la Fuente, Jorge
Caeiro, Francisco
Resumen
Primary Sjögren´s syndrome is a systemic and chronic autoimmune disease. Renal involvement may occur in up to 30% of patients. The incidence of tubulopathies ranges from 2.6 to 33%. They are manifested by defects in the urine concentration and hydroelectrolyte alterations, mainly distal tubular acidosis and exceptionally proximal tubular acidosis. These disorders can be associated with nephrocalcinosis and renal lithiasis. We report the case of a patient with primary Sjögren who presented proximal renal tubular acidosis associated with recurrent renal colic due to renal lithiasis and nephrocalcinosis. We highlight the importance of diagnosing renal tubular acidosis in patients with Sjögren´s syndrome that present alterations in urinary sediment and electrolyte disorders to avoid nephrocalcinosis and nephrolithiasis. Acidosis correction treatment aims to prevent the progression of the disorder and preserve renal function.