info:eu-repo/semantics/article
Plant serine protease inhibitors: Biotechnology application in agriculture and molecular farming
Fecha
2019-03Registro en:
Clemente, Marina; Corigliano, Mariana Georgina; Pariani, Sebastián A.; Sánchez López, Edwin Fernando; Sander, Valeria Analía; et al.; Plant serine protease inhibitors: Biotechnology application in agriculture and molecular farming; Molecular Diversity Preservation International; International Journal of Molecular Sciences; 20; 6; 3-2019; 1-21
1422-0067
CONICET Digital
CONICET
Autor
Clemente, Marina
Corigliano, Mariana Georgina
Pariani, Sebastián A.
Sánchez López, Edwin Fernando
Sander, Valeria Analía
Ramos Duarte, Víctor Andrés
Resumen
The serine protease inhibitors (SPIs) are widely distributed in living organisms like bacteria, fungi, plants, and humans. The main function of SPIs as protease enzymes is to regulate the proteolytic activity. In plants, most of the studies of SPIs have been focused on their physiological role. The initial studies carried out in plants showed that SPIs participate in the regulation of endogenous proteolytic processes, as the regulation of proteases in seeds. Besides, it was observed that SPIs also participate in the regulation of cell death during plant development and senescence. On the other hand, plant SPIs have an important role in plant defense against pests and phytopathogenic microorganisms. In the last 20 years, several transgenic plants over-expressing SPIs have been produced and tested in order to achieve the increase of the resistance against pathogenic insects. Finally, in molecular farming, SPIs have been employed to minimize the proteolysis of recombinant proteins expressed in plants. The present review discusses the potential biotechnological applications of plant SPIs in the agriculture field.