info:eu-repo/semantics/article
Adherence to antihypertensive drug treatment in Argentina: a multicenter study.Adherence to antihypertensive drugs in Argentina.
Fecha
2020-02Registro en:
Espeche, Walter; Salazar, Martin; Sabio, Rodrigo; Diaz, Alberto Alejandro; Leiva Sisnieguez, Carlos Enrique; et al.; Adherence to antihypertensive drug treatment in Argentina: a multicenter study.Adherence to antihypertensive drugs in Argentina.; Wiley Blackwell Publishing, Inc; Journal Of Clinical Hypertension; 2-2020; 1-7
1524-6175
CONICET Digital
CONICET
Autor
Espeche, Walter
Salazar, Martin
Sabio, Rodrigo
Diaz, Alberto Alejandro
Leiva Sisnieguez, Carlos Enrique
Olano, Daniel
Balbin, Eduardo
Renna, Nicolas Federico
Grosse, Pedro
Flores, Roberto A.
Lagos, Ana C.
Ferrero, Pablo
Poppe, Silvia
Risso Patron, Facundo
Sotnieczuk Stasiuk, Victor D.
Valentini, Elina
Cardozo, Jose Ricardo
Romano, Jose R.
Parodi, Roberto
Carbajal, Horacio
Resumen
Adherence to antihypertensive medication is an important challenge that doctors often face in the treatment of hypertension. Good adherence is crucial to prevent cardiovascular complications. In consequence, the present study aimed at determining the prevalence of adherence to antihypertensive treatment and identifying associated clinical variables. A multicenter cross-sectional study was conducted in 12 cities of Argentina. A systematic sampling was performed in order to select patients with hypertension and under pharmacological treatment for at least 6 months. Physicians took three BP measurements, and the level of adherence was assessed using the self-administered Morisky questionnaire (MMAS-8). Participants were classified into three levels of adherence: high adherence—MMAS score of 8; medium adherence—MMAS scores of 6 to <8; and low adherence—MMAS scores of <6. A total of 1111 individuals (62 ± 12 years old, women 49.4%) were included in the present analysis; 159 (14.3%), 329 (29.6%) and 623 (56.1%) patients had low, medium, and high adherence, respectively. The prevalence of controlled hypertension increased only in high adherent patients: 42.8%, 42.2%, and 64.5% for low, medium, and high adherence groups, respectively. Similarly, systolic BP was lower only in the high adherence group. High educational level (OR 3.47, 95% CI 2.68-4.49) and diuretic treatment (OR 0.64, 95% CI 0.47-0.88) were independent predictors of high adherence. In conclusion, more than a half of treated hypertensive patients had a high level of adherence. These patients had lower BP values and higher control levels. A high educational level predicts high adherence.