info:eu-repo/semantics/article
Egg yolk IgY antibodies: A therapeutic intervention against group A rotavirus in calves
Fecha
2015-12Registro en:
Vega, Celina Guadalupe; Bok, Marina; Saif, L.; Fernandez, F.; Parreño, Gladys Viviana; Egg yolk IgY antibodies: A therapeutic intervention against group A rotavirus in calves; Elsevier; Research in Veterinary Science; 103; 12-2015; 1-10
0034-5288
CONICET Digital
CONICET
Autor
Vega, Celina Guadalupe
Bok, Marina
Saif, L.
Fernandez, F.
Parreño, Gladys Viviana
Resumen
Bovine group A rotavirus (RVA) is considered the major cause of diarrhea in intensively reared neonatal calves. Chicken egg yolk antibodies (IgY) are efficient in protecting neonatal calves from RVA diarrhea; however, the value of this intervention in calves once diarrhea has appeared is unclear. The aim of the present study was to evaluate the application of RVA-specific IgY as a passive treatment in those cases. The experimental groups were: G1 = RVA-specific IgY treatment; G2 = no Ab treatment; and G3 = colostrum deprived + no Ab treatment. IgY treatment significantly reduced virus shedding, diarrhea duration and severity compared to G2 and G3 calves. However, it caused a partial suppression of systemic Ab responses to RVA that could be associated with less severe diarrhea. The oral treatment with IgY for 7 days was associated with significantly higher antibody secreting cell responses in the calves compared with other groups of animals.