article
Geometrical guidance and trapping transition of human sperm cells
Fecha
2014Registro en:
Autor
Guidobaldi, Héctor Alejandro
Jeyaram, Y.
Berdakin, Ivan
Moshchalkov, V. V.
Condat, Carlos Alberto
Marconi, Verónica Iris
Giojalas, Laura Cecilia
Silhanek, Alejandro V.
Institución
Resumen
The guidance of human sperm cells under confinement in quasi-2D microchambers is investigated using a purely physical method to control their distribution. Transport property measurements and simulations are performed with diluted sperm populations, for which effects of geometrical guidance and concentration are studied in detail. In particular, a trapping transition at convex angular wall features is identified and analyzed. We also show that highly efficient microratchets can be fabricated by using curved asymmetric obstacles to take advantage of the spermatozoa specific swimming strategy.