dc.contributor | https://orcid.org/0000-0003-1324-4488 | |
dc.creator | Muñoz Carrillo, José Luís | |
dc.creator | Castro García, Flor Pamela | |
dc.creator | Gutiérrez Coronado, Oscar | |
dc.creator | Moreno García, María Alejandra | |
dc.creator | Contreras Cordero, Juan Francisco | |
dc.date.accessioned | 2019-02-27T18:42:31Z | |
dc.date.available | 2019-02-27T18:42:31Z | |
dc.date.created | 2019-02-27T18:42:31Z | |
dc.date.issued | 2017-12-20 | |
dc.identifier | 978-953-51-3692-7 | |
dc.identifier | http://localhost/xmlui/handle/20.500.11845/680 | |
dc.identifier | https://doi.org/10.48779/g2ys-yx96 | |
dc.description.abstract | Pathogen infections are recognized by the immune system, which consists of two types
of responses: an innate immune response and an antigen-specific adaptive immune
response. The innate response is characterized by being the first line of defense that occurs
rapidly in which leukocytes such as neutrophils, monocytes, macrophages, eosinophils,
mast cells, dendritic cells, etc., are involved. These cells recognize the pathogen-associated
molecular patterns (PAMPs), which have been evolutionarily conserved by the diversity
of microorganisms that infect humans. Recognition of these pathogen-associated molecular
patterns occurs through pattern recognition receptors such as Toll-like receptors and
some other intracellular receptors such as nucleotide oligomerization domain (NOD),
with the aim of amplifying the inflammation and activating the adaptive cellular immune
response, through the antigenic presentation. In the present chapter, we will review the
importance of the main components involved in the innate immune response, such as different
cell types, inflammatory response, soluble immune mediators and effector mechanisms
exerted by the immune response against bacteria, viruses, fungi, and parasites; all
with the purpose of eliminating them and eradicating the infection of the host. | |
dc.language | eng | |
dc.publisher | IntechOpen | |
dc.relation | generalPublic | |
dc.relation | https://www.intechopen.com/books/physiology-and-pathology-of-immunology/physiology-and-pathology-of-innate-immune-response-against-pathogens | |
dc.rights | http://creativecommons.org/licenses/by-nc-sa/3.0/us/ | |
dc.rights | Atribución-NoComercial-CompartirIgual 3.0 Estados Unidos de América | |
dc.source | Nima Rezaei (Coord.), Physiology and Pathology of Immunology, Tehran University of Medical Sciences | |
dc.title | Physiology and Pathology of Innate Immune Response Against Pathogens | |
dc.type | info:eu-repo/semantics/bookPart | |