Colocalized delivery of rapamycin and paclitaxel to tumors enhances synergistic targeting of the PI3K/Akt/mTOR pathway

dc.creatorCarlos Alberto González Delgado
dc.date.accessioned2018-10-18T20:12:51Z
dc.date.accessioned2022-10-13T19:45:06Z
dc.date.available2018-10-18T20:12:51Z
dc.date.available2022-10-13T19:45:06Z
dc.date.created2018-10-18T20:12:51Z
dc.identifier15250016
dc.identifier10.1038/mt.2014.27
dc.identifierhttp://hdl.handle.net/11285/630309
dc.identifier22
dc.identifier7
dc.identifier1310
dc.identifier1319
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4207752
dc.publisherNature Publishing Group
dc.relationhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84903759913&doi=10.1038%2fmt.2014.27&partnerID=40&md5=8f19aaba3365f84d7c33f08916ec8eb8
dc.relationInvestigadores
dc.relationEstudiantes
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceMolecular Therapy
dc.subjectmammalian target of rapamycin
dc.subjectnanoparticle
dc.subjectpaclitaxel
dc.subjectphosphatidylinositol 3 kinase
dc.subjectprotein kinase B
dc.subjectrapamycin
dc.subjectpaclitaxel
dc.subjectphosphatidylinositol 3 kinase
dc.subjectprotein kinase B
dc.subjectrapamycin
dc.subjecttarget of rapamycin kinase
dc.subjectanimal experiment
dc.subjectanimal model
dc.subjectanimal tissue
dc.subjectantineoplastic activity
dc.subjectbreast cancer
dc.subjectcancer inhibition
dc.subjectconference paper
dc.subjectcontrolled study
dc.subjectdrug delivery system
dc.subjectdrug potentiation
dc.subjectdrug tumor level
dc.subjectfemale
dc.subjectin vitro study
dc.subjectliver
dc.subjectmouse
dc.subjectnanoencapsulation
dc.subjectnanopharmaceutics
dc.subjectnonhuman
dc.subjectparticle size
dc.subjectprotein phosphorylation
dc.subjectprotein targeting
dc.subjectspleen
dc.subjectanimal
dc.subjectapoptosis
dc.subjectcell proliferation
dc.subjectdrug effects
dc.subjecthuman
dc.subjectMammary Neoplasms, Animal
dc.subjectMCF 7 cell line
dc.subjectmetabolism
dc.subjectnude mouse
dc.subjectsignal transduction
dc.subjecttumor cell line
dc.subjectAnimalia
dc.subjectMus
dc.subjectAnimals
dc.subjectApoptosis
dc.subjectCell Line, Tumor
dc.subjectCell Proliferation
dc.subjectFemale
dc.subjectHumans
dc.subjectMammary Neoplasms, Animal
dc.subjectMCF-7 Cells
dc.subjectMice
dc.subjectMice, Nude
dc.subjectPaclitaxel
dc.subjectPhosphatidylinositol 3-Kinases
dc.subjectProto-Oncogene Proteins c-akt
dc.subjectSignal Transduction
dc.subjectSirolimus
dc.subjectTOR Serine-Threonine Kinases
dc.titleColocalized delivery of rapamycin and paclitaxel to tumors enhances synergistic targeting of the PI3K/Akt/mTOR pathway
dc.typeConferencia


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