The postgraduate trends in knowledge management in Ibero-America are compared, from the consideration of eleven programs, related to the countries: Venezuela, Spain, Mexico, Chile, Colombia, Argentina and Puerto Rico. It is a qualitative study, focused on the comparison of curricular profiles, approaches and contents of the programs, which were recorded in tables, as an instrument for gathering and analyzing information. The main results point to the presence of diverse approaches of how knowledge management is understood, from linking it with educational, technological, and innovation processes to properly business and productive processes, relating in turn to the thematic-curricular orientation of the Faculties and Universities that manage them. Regarding the profiles of graduates, the competences oscillate between the management of projects, coordination of technological processes to support the creation, organization and transfer of knowledge, mediation and negotiation. In conclusion, there is a high potential for cooperation and academic collaboration among postgraduate programs, as a substantive element that generates synergies for the development of research projects and collective publishing initiatives.