Yield is a complex trait and is under the control of multiple genes in which the environment interfere on the phenotype. The estimation of genetic components, including non-allelic interactions acquire a great importance on the breeding of a crop. The objective of this study was to estimate the genetic parameters for yield, using generation means analysis (P , P , F , F , BC and BC ) derived from the cross of Pimenton Serrano and Aji Cayenne 958 (inbreed lines of Capsicum annuum). The analysis revealed that additive, dominance and the non-allelic interactions components were significantly for the phenotypic expression, indicating the need for a four-parameters model. Additive by additive [i] effects revealed significance for fruit weight. Recessive or double recessive epistasis, was found. Finally, a breeding program based on recurrent selection to increase the average yield in a pepper (Capsicum annuum) population can be used, due to the epistatic interaction can be effectively exploited through the hybridization among promissory lines. 1 2 1 2 1 2