Mammary gene expressions and oxidative indicators in ruminal fluid, blood, milk, and mammary tissue of dairy goats fed a total mixed ration containing piper meal (Piper betle L.)

Mammary gene expressions and oxidative indicators in ruminal fluid, blood, milk, and mammary tissue of dairy goats fed a total mixed ration containing piper meal (Piper betle L.)

dc.creatorPurba, Rayudika Aprilia Patindra;#0000-0003-4672-1455
dc.creatorPaengkoum, Siwaporn;#0000-0001-8529-3452
dc.creatorYuangklang, Chalermpon;#0000-0002-3844-1691
dc.creatorPaengkoum, Pramote;#0000-0003-2606-9965
dc.creatorZeidan Mohamed Salem, Abdelfattah; 274697
dc.creatorLiang, Juan Boo;#0000-0001-6024-0856
dc.creatorPurba, Rayudika Aprilia Patindra
dc.creatorPaengkoum, Siwaporn
dc.creatorYuangklang, Chalermpon
dc.creatorPaengkoum, Pramote
dc.creatorZeidan Mohamed Salem, Abdelfattah
dc.creatorLiang, Juan Boo
dc.date2022-09-01T02:44:24Z
dc.date2022-09-01T02:44:24Z
dc.date2022-01-03
dc.date.accessioned2022-10-13T00:30:47Z
dc.date.available2022-10-13T00:30:47Z
dc.identifier1828-051X
dc.identifierhttp://hdl.handle.net/20.500.11799/113352
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4156403
dc.descriptionThe study evaluated the effect of piper meal which contains flavonoids, essential oils, and phenolic acids on the activity of antioxidant enzymes such as superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT), and as well as oxidative stress indicators such as 1,1-diphenyl-2-picrylhydrazyl-scavenging activity and thiobarbituric acid-reactive substances (TBARS) in the ruminal fluid, mammary tissue, milk, and blood of lactating goats. Fourteen early lactating Saanen goats (body weight, 44 ± 2.51 kg; 14 ± 3 days in milk) were allotted in equal number to two experimental groups, each received one of the two total mixed rations: control (CON) diet (containing 0% piper meal) and CPM diet (CON diet containing 1.3% piper meal per kg dry matter). Compared with goats fed the CON diet, those fed CPM diet had similar 1,1-diphenyl-2-picrylhydrazyl-scavenging, GPx and CAT activity in ruminal fluid, mammary tissue, milk, and blood; however, those samples had increased SOD activity. Dietary CPM diet had a tendency to decrease TBARS production in ruminal fluid, mammary tissue, milk, and plasma by about 2.4, 1.2, 1.1, and 1.4 folds, respectively. Furthermore, alleviated values of TBARS were associated with dwindling mRNA expression of κ light polypeptide gene enhancer in nuclear factor kappa B subunit 1 (NFKB1) but greater expression of SOD1, SOD2, SOD3, and nuclear factor (erythroid-derived 2)-like 2 (NFE2L2) in mammary tissue. Our findings showed that the inclusion of 13.0 g piper meal in per kg diet (CPM) can improve the oxidative status of Saanen goats in early lactation.
dc.languageeng
dc.languageeng
dc.publisherItalian Journal of Animal Science
dc.relation21
dc.relationhttps://doi.org/10.1080/1828051X.2021.2007173
dc.rightsopenAccess
dc.rightshttp://creativecommons.org/licenses/by/4.0
dc.rightshttp://creativecommons.org/licenses/by/4.0
dc.subjectsynergistic nutritional compounds
dc.subjectAntioxidant system
dc.subjectlactation
dc.subjectsynergistic nutritional compounds
dc.subjectAntioxidant system
dc.subjectlactation
dc.subjectCIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA
dc.subjectCIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA
dc.titleMammary gene expressions and oxidative indicators in ruminal fluid, blood, milk, and mammary tissue of dairy goats fed a total mixed ration containing piper meal (Piper betle L.)
dc.titleMammary gene expressions and oxidative indicators in ruminal fluid, blood, milk, and mammary tissue of dairy goats fed a total mixed ration containing piper meal (Piper betle L.)
dc.typeArtículo
dc.typeArtículo
dc.typearticle


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