Evaluation of a Salivary Cortisol ELISA Kit in a Critical Obstetrical Unit

dc.creatorReyes Mendoza, Luis Emilio;x1340677
dc.creatorLAYTON TOVAR, CRISTIAN FABIAN; 554062
dc.creatorAndrés Osorio, Emmanuel Alejandro;x1354842
dc.creatorMendieta Zerón, Hugo; 45175
dc.creatorReyes Mendoza, Luis Emilio
dc.creatorLAYTON TOVAR, CRISTIAN FABIAN
dc.creatorAndrés Osorio, Emmanuel Alejandro
dc.creatorMendieta Zerón, Hugo
dc.date2021-09-11T05:28:45Z
dc.date2021-09-11T05:28:45Z
dc.date2017
dc.date.accessioned2022-10-13T00:13:04Z
dc.date.available2022-10-13T00:13:04Z
dc.identifier1994-7925
dc.identifierhttp://hdl.handle.net/20.500.11799/110882
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4154300
dc.descriptionBackground and Objective: In recent years the use of saliva samples for the diagnosis of several clinical entities has been constantly increasing. The aim of this study was to describe the correlation between salivary and serum cortisol levels with the bleeding volume in cases of obstetrical hemorrhage grades III-IV. Methodology: This was a pilot prospective cross-sectional study. Two groups were conformed, 1) Puerperal women with grade III-IV obstetric hemorrhage and (2) Healthy puerperal women. During the first 8 h of admission to the Obstetrical-ICU or Hospitalization Service, a blood and saliva samples for cortisol measures were taken simultaneously. Relationships between the measured variables were assessed using Spearman correlations. All tests were performed with the SPSS ver. 23 statistical software program (IBM SPSS Statistics Armonk, NY: IBM Corp.). Results: Eight patients were included, 4 with hemorrhage (mean age 31 years, SE: 2) and 4 with healthy pregnancies (mean age 26 years, SE: 2.7). Within the subgroup of patients with hemorrhage, the Spearman correlation for saliva and serum cortisol was of 0.800 (p = 0.2). The negative correlation between salival cortisol and hemorrhage was high but without reaching statistical significance (r2 = -0.800, p<0.200). Conclusion: The saliva cortisol determination through an ELISA kit has a high correlation with serum cortisol in case of obstetric hemorrhage Grades III-IV which give a glimpse to think about a possible failure in the ACTH-cortisol axis.
dc.languageeng
dc.publisherResearch Journal of Obstetrics and Gynecology
dc.relation10
dc.relation1
dc.relation10.3923/rjog.2017.11.16
dc.rightsopenAccess
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0
dc.subjectSalivary cortisol Elisa Kit
dc.subjectEvaluation
dc.subjectCritical obstetrical unit
dc.subjectMEDICINA Y CIENCIAS DE LA SALUD
dc.subjectMEDICINA Y CIENCIAS DE LA SALUD
dc.titleEvaluation of a Salivary Cortisol ELISA Kit in a Critical Obstetrical Unit
dc.typeArtículo


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