Alterations to embryonic development and teratogenic effects induced by a hospital effluent on Cyprinus carpio oocytes

dc.creatorLuja Modragón, Marlenee;x1357860
dc.creatorGómez Olivan, Leobardo Manuel; 201091
dc.creatorSAN JUAN REYES, NELY; 413086
dc.creatorISLAS FLORES, HARIZ; 265074
dc.creatorOROZCO HERNANDEZ, JOSE MANUEL; 857827
dc.creatorHEREDIA GARCIA, GERARDO; 857838
dc.creatorGALAR MARTINEZ, MARCELA; 121303
dc.creatorDUBLAN GARCIA, OCTAVIO; 36251
dc.creatorLuja Modragón, Marlenee
dc.creatorGómez Olivan, Leobardo Manuel
dc.creatorSAN JUAN REYES, NELY
dc.creatorISLAS FLORES, HARIZ
dc.creatorOROZCO HERNANDEZ, JOSE MANUEL
dc.creatorHEREDIA GARCIA, GERARDO
dc.creatorGALAR MARTINEZ, MARCELA
dc.creatorDUBLAN GARCIA, OCTAVIO
dc.date2019-01-29T15:46:04Z
dc.date2019-01-29T15:46:04Z
dc.date2019-01-08
dc.date.accessioned2022-10-12T23:29:01Z
dc.date.available2022-10-12T23:29:01Z
dc.identifier0048-9697
dc.identifierhttp://hdl.handle.net/20.500.11799/98676
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4149721
dc.descriptionArtículo indizado en revista internacional
dc.descriptionand diverse pharmaceuticals are noteworthy that can affect organisms if they are not properly removed from the effluents. The hospital effluent evaluated in the present study came from IMSS (Instituto Mexicano del Seguro So- cial) Clinic 221 in downtown Toluca, State of Mexico, a secondary care facility. The contaminants identified in hospitals have been associated with deleterious effects on aquatic organisms; however, it is necessary to continue with more studies in order to be able to regulate the production of said contaminants which are generally dumped into the city sewage system. The present study had the purpose of evaluating the alterations to embry- onic development and teratogenic effects on oocytes Cyprinus carpio after exposure to different proportions of hospital effluent. For said purpose, the physicochemical properties of the effluent were determined. Concentra- tions of the main microcontaminants were also determined. An embryolethality study out and the determination of the main alterations to embryonic development and teratogenic effects produced, due to exposure of C. carpio at different proportions of the effluent, were carried out. The results showed that the physicochemical properties were within the values permitted by Mexican regulation; however, the presence of contaminants such as NaClO metals, anti-biotics, anti-diabetics, non-steroidal anti-inflammatory drugs, hormones and beta-blockers, was de- tected. Lethal concentration 50 was 5.65% and the effective concentration for malformations was 3.85%, with a teratogenic index of 1.46. The main teratogenic alterations were yolk deformation, scoliosis, modified chorda structure, tail malformation, fin deformity and mouth hyperplasia. A high rate of hatching delay was observed. The results suggest that the hospital effluent under study is capable of inducing embryotoxicity and teratogenic- ity in oocytes of C. carpio.
dc.descriptionConsejo Nacional de Ciencia y Tecnología
dc.languageeng
dc.publisherScience of the Total Environment
dc.rightsopenAccess
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0
dc.subjectembryonic development
dc.subjectteratogenic effects
dc.subjectCyprinus carpio
dc.subjecthospital effluent
dc.subjectBIOLOGÍA Y QUÍMICA
dc.titleAlterations to embryonic development and teratogenic effects induced by a hospital effluent on Cyprinus carpio oocytes
dc.typeArtículo
dc.typearticle


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