| dc.creator | TIAN,LINGXING | |
| dc.creator | YANG,WEIJIE | |
| dc.creator | CHEN,XIAOQING | |
| dc.creator | XIE,YIXI | |
| dc.date | 2011-01-01 | |
| dc.date.accessioned | 2017-03-07T16:38:17Z | |
| dc.date.available | 2017-03-07T16:38:17Z | |
| dc.identifier | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072011000200003 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/405021 | |
| dc.description | The distribution behavior of ofloaxcin (OFLX) enantiomers in a two-phase system was examined using a new mixed complex chiral selector consisting of di(2-ethylhexyl) phosphoric acid (D2EHPA) and two tartaric acid derivatives with n-octanol as diluents. The influence of composition of mixed complex chiral selector, initial concentration of OFLX, pH of aqueous phase and temperature was investigated. A maximum enantioselectivity of 2.43 was obtained when the molar concentration ratio of L-(-)-DBTA to L-(-)-DTTA is 2:3 L-(-)-DTTA concentration 0.18 mol/L, L-(-)-DBTA concentration 0.12mol/L) and the pH of aqueous phase is 6.86 at 25°C, with Dd and Dl up to a relative high value of 10.2 and 4.20, respectively. The results indicated a useful way of searching new efficient chiral selectors and it was proved also helpful to optimize the extraction systems and realize the large-scale production of the pure isomer of racemic mixtures with extraction methods. | |
| dc.format | text/html | |
| dc.language | en | |
| dc.publisher | Sociedad Chilena de Química | |
| dc.source | Journal of the Chilean Chemical Society v.56 n.2 2011 | |
| dc.subject | Enantioselective extraction | |
| dc.subject | ofloxacin enantiomers | |
| dc.subject | D2EHPA | |
| dc.subject | tartaric acid derivative | |
| dc.subject | complex chiral selectors | |
| dc.title | ENANTIOSELECTIVE EXTRACTION OF RACEMIC OFLOXACIN BY DI(2-ETHYLHEXYL)PHOSPHORIC ACID AND TARTARIC ACID DERIVATIVES AS MIXED COMPLEX CHIRAL SELECTORS | |
| dc.type | Artículos de revistas | |
