dc.creatorRiquelme O,Raúl
dc.creatorRiquelme O,Mauricio
dc.creatorRioseco Z,María Luisa
dc.creatorInzunza P,Carlos
dc.creatorContreras G,Cristian
dc.creatorGómez V,Yarella
dc.creatorRiquelme D,Javier
dc.date2011-03-01
dc.date.accessioned2017-03-07T16:37:59Z
dc.date.available2017-03-07T16:37:59Z
dc.identifierhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000300006
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/404928
dc.descriptionBackground: Pandemic flu (H1N1 ) strongly affected southern Chile during2009. Aim: To report the logistic and organizational changes implemented at a regional hospital to face the pandemic. Material and Methods: All patients with flu like disease that were hospitalized, were prospectively enrolled at the Puerto Montt hospital. A nasopharyngeal aspirate was obtained in all for influenza virus A and B direct immunofluorescence and polymerase chain reaction (PCR). All epidemiological and clinical data of patients were recorded. Results: Between May 29 and July 7, 2009, 184 adults were admitted to the hospital and in 117patients aged 41 ± 18 years (56% females ), direct immunofluorescence was positive for influenza. In 67 of these patients PCR did not confirm the disease. These unconfirmed patients had a mean age of 49 ± 19 years (p < 0.01, compared with confirmed cases) and had a lower frequency of fever, rhinorrhea and chills. No significant differences in the incidence of community acquired pneumonia or chest X ray findings were observed between confirmed and unconfirmed cases. Hospital stay was over 15 days in 14% of confirmed cases and 5% of unconfirmed cases (p = 0.03). Fifteen patients, aged 53 ± 18 years, died. Conclusions: Low sensibility of direct immunofluorescence and delay in obtaining PCR confirmation of influenza posed a problem for the management of these patients.
dc.formattext/html
dc.languagees
dc.publisherSociedad Médica de Santiago
dc.sourceRevista médica de Chile v.139 n.3 2011
dc.subjectFluorescent antibody technique
dc.subjectH1N1 virus
dc.subjectInfluenza
dc.subjecthuman
dc.titleImpacto clínico de la influenza A H1N1 pandémica en el hospital de Puerto Montt, Chile
dc.typeArtículos de revistas


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