Dissertação
As alterações da marcha como fatores preditores de depressão incidente: uma revisão sistemática
Fecha
2020-07-30Autor
Silva, Marília Gomes da
Institución
Resumen
Introduction: Depression is a multifactorial disorder that affects people of all ages and both sexes, associated with emotional and motor disorders, thus impairing the quality of life of these individuals. Objective: To verify whether changes in gait parameters can predict the risk of incident depression. Methodology: The study was characterized as a systematic review, where a search was performed in four databases (PubMed, PsycINFO, Web of Science and SPORTDiscus), including longitudinal cohort articles, with a follow-up of at least one year, written in Portuguese, English or Spanish, which evaluated depression and gait at baseline and the subsequent risk of incident depression according to the alteration of some gait parameter. The risk of bias in the studies was assessed using the NewCastle Ottawa Scale (NOS). Random effects meta-analyses were performed, calculating the risk in adjusted and unadjusted odds ratios (OR) along with the confidence interval. Heterogeneity was evaluated using the I² statistic. Potential sources of heterogeneity (gender, age and follow-up) were explored by meta-regressions. Results: 7 studies were included, where 21,038 participants were evaluated. During the analysis of unadjusted gait speed, the slower people had a 2.88 times greater risk of developing depression, while in the adjusted one, a risk of 1.63. When investigating the speed before and after the potential moderators (gender, age and follow-up), it was noticed that none of the factors evaluated moderated the association between changes in gait and risk of incident depression. The assessment of the quality of the studies achieved a mean score of 7.5 (Standard Deviation = 0.5). Conclusion: A slower walking speed is associated with a higher risk of developing depression.