It is known that there exists close relationship between cranial capacity and size of the brain. Several studies have estimated the cranial capacity, which indirectly reflects the brain volume in different populations. The aim of this study was to estimate cranial capacity of a particular age group of population of Madhya Pradesh. This study was carried out on 400 healthy 20-25 year old (200 male and 200 female) individuals of Madhya Pradesh state of India, by using linear dimensions of head (Lee Pearson's formula). The mean cranial capacity and SD in males &amp; females were 1380.52±94.63 cc and 1188.75±91.16 cc respectively. This study has shown a significant (p<0.05) difference between male and female population, being higher in males than in females.