On the basis of the revision of the type material of Aspiculuris ackerti Kruidenier & Mehra, 1959, and new specimens collected from Neotoma nelsoni Goldman, 1905 (Rodentia: Cricetidae), in Veracruz, Mexico, we herein to which A. ackerti is transferred as Lamotheoxyuris ackerti This new genus differs from all other genera included in 1) mouth surrounded by six lips; 2) extension of lateral alae describe a new genus (Lamotheoxyuris n. gen.), (Kruidener & Mehra, 1959) n. gen., n. comb. Heteroxynematinae by the following main traits: reduced; and 3) lack of caudal alae.