Rol del riñón en la hipertensión sal-sensible

dc.creatorARDILES,LEOPOLDO
dc.creatorMEZZANO,SERGIO
dc.date2010-07-01
dc.date.accessioned2017-03-07T16:29:02Z
dc.date.available2017-03-07T16:29:02Z
dc.identifierhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700012
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/402368
dc.descriptionAn important proportion of patients with essential hypertension are salt sensitive, defined as those who experience signifcant blood pressure changes according to the amount of salt intake. They have a disturbance in the pressure induced natriuresis mechanism and their kidneys have functional and morphological alterations con-sistent with an acquired tubulointerstitial alteration, afferent arteriole damage and alteration of peritubular capillaries. All these alterations lead to disturbances in sodium load excretion under normal pressures. There is also an associated activation of kidney vasoconstrictor/salt retaining systems and a reduction in the vasodilator/ salt eliminating mechanisms. These alterations, that originate early in life, generate a new blood pressure level, that corrects natriuresis at the expense of a sustained hypertension.
dc.formattext/html
dc.languagees
dc.publisherSociedad Médica de Santiago
dc.sourceRevista médica de Chile v.138 n.7 2010
dc.subjectHypertension, renal
dc.subjectKidney diseases
dc.subjectNatriuresis
dc.titleRol del riñón en la hipertensión sal-sensible
dc.typeArtículos de revistas


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