dc.creatorCavalcanti,Ully Dias Nascimento Távora
dc.creatorBaratella Evêncio,Liriane
dc.creatorEvêncio Neto,Joaquim
dc.creatorCastro,Raul Manhães de
dc.creatorCardona,Aryana Soares
dc.creatorMelo,Marina Lins Maymone de
dc.creatorLins,Rafael Claudino
dc.date2009-09-01
dc.date.accessioned2017-03-07T16:20:30Z
dc.date.available2017-03-07T16:20:30Z
dc.identifierhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300041
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/399922
dc.descriptionThe TMJ has been to the Dental community a key point in the search of knowledge, being it part of the temporomandibular joint complex and of the estomatognathic system which are in charge of the mastication, speech, swallowing, as well as participation in breathing and taste perception. For the majority of the women in serious state of depression, which do not respond psychotherapeutic treatment, pharmacological treatment it's applied. The antidepressants serotonin selective reuptake inhibitors (SSRIs) are the most recommended in these cases. The teratogenic effect of the SSRIs is considered controversial, studies done with women who used these drugs during the pregnancy showed that the respiratory and central nervous systems are the most affected, was also recorded a deficit of body growth and the decrease of the encephalon and skull measures. In the present study, our goal was to assess whether the administration of Fluoxetine during the pregnancy modified the embryology and morphology of the TMJ of rats. For that, 16 Wistar female rats from the Nutrition Department of the UFPE vivarium were selected; 8 for the control group, which received daily 0.9% of saline in subcutaneous dose of 10ml/g, with schedules previously established after daily weighing and 8 for the experimental one that were treated with fluoxetine hydrochloride with the dose of 10mg/Kg in a volume 10ml/g of weight, were injected subcutaneously with the same standards established for the control group. It was observed, with this dose that the embryological development of the TMJ, especially of the mandibular condyle, does not present any difference between the degree of maturation of the tissue that forms the TMJ, especially of the condyle between the treated and control groups.
dc.formattext/html
dc.languageen
dc.publisherSociedad Chilena de Anatomía
dc.sourceInternational Journal of Morphology v.27 n.3 2009
dc.subjectTMJ
dc.subjectMandibular condyle
dc.subjectSerotonin
dc.subjectFluoxetine
dc.subjectDevelopment
dc.titleMorphological Aspects of the Embryonic Development of the TMJ in Rats (Rattus norvegicus albinus) Treated With Fluoxetine
dc.typeArtículos de revistas


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