Artículos de revistas
SYNTHESIS OF 3 SUBSTITUTED ISOQUINOLIN-1-YL-2-(CYCLOALK-2-ENYLIDENE) HYDRAZINES AND THEIR ANTIMICROBIAL PROPERTIES
Autor
MANIVEL,P
MOHANA ROOPAN,S
SATHISH KUMAR,R
NAWAZ KHAN,F
Institución
Resumen
New hydrazine derivatives were synthesized via reaction between 1, 3 cyclic diketones and hydrazinoisoquinohne derivatives. The reaction proceeded smoothly in ethanol under reflux temperature and furnished products in excellent yields (76-87%). The products have been purified and fully characterized by spectroscopy techniques. The compounds 8a-c showed good bacterial inhibition against Bacillus cerus and 8d-f showed good antifungal activity against Candida albicans.