Alot has been reported about variation of palmaris longus muscle in journals and conventional textbooks. The incidence of palmaris longus muscle absence among people of the six geo-political zones of Nigeria was evaluated using 600 subjects. 31.25% (187 subjects) lack palmaris longus muscleon either of the forearms. 12.5% (75 subjects) shows unilateral absence and 18.75% (112 subjects) shows bilateral absence. 25% (150) of subjects lacks palmaris longus muscleon their right forearms while 25% also lacks it on their left forearms. 6% (37) shows double tendons of palmaris longus muscleon both forearms. Highest incidence of absence was recorded among people of South-West zone.