dc.creatorLópez-Rodríguez,Raimundo
dc.creatorGarcía-González,Jorge
dc.creatorCampos-Franco,Joaquín
dc.creatorMallo-González,Nieves
dc.creatorAlende-Sixto,María Rosario
dc.date2007-07-01
dc.date.accessioned2017-03-07T15:51:48Z
dc.date.available2017-03-07T15:51:48Z
dc.identifierhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000700012
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/392121
dc.descriptionWegener's granulomatosis is a systemic necrotizing vasculitis that affects medium size and small vessels. Neurological involvement occurs in 22% to 54% of patients, mainly in the form of mononeuritis multiplex. Central nervous system involvement is reported in only 2% to 8% of the cases. We report a 42-year-old male who presented with headache, diplopia, third and sixth cranial nerve palsies and ¡eft eye amaurosis associated to mass located in the ¡eft Meckel cavum and diffuse meningeal involvement. A biopsy of the mass disclosed a chronic granulomatous necrotizing inflammation with Langhans giant cells. A chest CAT scan showed three cavitated lung nodules and ANCA antibodies were positive in a titer of 1:80. Treatment with steroid and cyclophosphamide was started and cranial nerve palsies resolved and the number and size of lung nodules decreased. The patient was lost from follow up
dc.formattext/html
dc.languagees
dc.publisherSociedad Médica de Santiago
dc.sourceRevista médica de Chile v.135 n.7 2007
dc.subjectMeningitis aseptic
dc.subjectVasculitis
dc.subjectWegener granulomatosis
dc.titleManifestaciones neurológicas de la granulomatosis de Wegener: Caso clínico
dc.typeArtículos de revistas


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