dc.creatorRigotti R,Attilio
dc.creatorArteaga Ll,Antonio
dc.creatorMaiz G,Alberto
dc.date2006-05-01
dc.date.accessioned2017-03-07T15:38:15Z
dc.date.available2017-03-07T15:38:15Z
dc.identifierhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000500014
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/388516
dc.descriptionPrimary and secondary prevention trials have clearly demonstrated that lowering serum cholesterol levels with statins reduces the incidence of cardiovascular events. Recent studies plus post hoc analysis of previous clinical trials show that risk reduction is proportional to the magnitude of LDL cholesterol lowering. Therefore, new recommendations of the National Cholesterol Education Program (USA) have defined a category of patients with very high cardiovascular risk, who should achieve serum LDL cholesterol levels below 70 mg/dl. This proposal will require new and more efficient pharmacologic strategies to attain the increasingly strict therapeutic goals for LDL cholesterol. This article reviews the clinical studies that support the use of intensive lipid lowering therapy to reduce cardiovascular risk. An effective reduction of serum cholesterol can be obtained using statins in high doses or a combination of hypolipidemic drugs with different mechanisms of action
dc.formattext/html
dc.languagees
dc.publisherSociedad Médica de Santiago
dc.sourceRevista médica de Chile v.134 n.5 2006
dc.subjectHydroxymethylglutaryl-CoA reductase inhibitors
dc.subjectHypercholesterolemia
dc.titleTerapia hipolepemiante intensiva en el manejo del riesgo cardiovascular ateroesclerótico
dc.typeArtículos de revistas


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