| dc.creator | Roa E,ván | |
| dc.creator | de Aretxabala U,Xabier | |
| dc.creator | Araya O,Juan C | |
| dc.creator | Villaseca H,Miguel | |
| dc.creator | Roa S,Juan | |
| dc.creator | Burgos S,Luis | |
| dc.creator | Guzmán G,Pablo | |
| dc.date | 2001-09-01 | |
| dc.date.accessioned | 2017-03-07T15:33:12Z | |
| dc.date.available | 2017-03-07T15:33:12Z | |
| dc.identifier | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000900006 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/387085 | |
| dc.description | Background: The usefulness of surgery in the treatment of gallbladder cancer has not been clearly established. The benefits of chemo and radiotherapy are similarly dubious. Aim: To report the pathological findings in patients subjected to surgical reinterventions for gallbladder cancer. Patients and methods: We report 54 patients with gallbladder cancer that were subjected to a second surgical intervention for resection of liver segments IVb and V and lymph nodes corresponding to the liver hilar, portal, peripancreatic, celiac artery and periaortic territories. Thirteen of these patients were subjected to preoperative chemo-radiotherapy (4500 Gy and 5-fluouracil 500 mg/m²). Results: Lymph node metastases were found in 25 and 38%, and liver metastases in 25 and 28% of patients with or without chemo-radiotherapy respectively. The most frequent pathological findings attributed to radiation in the liver were fatty infiltration in 75% of cases, vascular transformation in 83% of cases and minimal periportal lymphocyte infiltration in 40% of cases. Lymph nodes were atrophic in 67% of cases and had foci of cortical necrosis in 46% of cases. Three cases had regional lymph node and liver metastases. Most tumor cells were viable. Conclusions: No differences in the number of lymph node or liver metastases were observed between patients with and without chemo-radiotherapy. No effect of the treatment on residual tumor was observed either (Rev Méd Chile 2001; 129: 1013-20 | |
| dc.format | text/html | |
| dc.language | es | |
| dc.publisher | Sociedad Médica de Santiago | |
| dc.source | Revista médica de Chile v.129 n.9 2001 | |
| dc.subject | Chemotherapy, adjuvant | |
| dc.subject | Gallbladder neoplasms | |
| dc.subject | Radiotherapy, adjuvant | |
| dc.subject | Surgical procedures | |
| dc.title | Hallazgos en reintervenciones quirúrgicas por cáncer de la vesícula biliar en pacientes con y sin quimio-radiación preoperatoria | |
| dc.type | Artículos de revistas | |
