| dc.creator | Castillo C,José Luis | |
| dc.creator | Cea M,Gabriel | |
| dc.creator | Cartier R,Luis | |
| dc.creator | Verdugo L,Renato | |
| dc.date | 2001-07-01 | |
| dc.date.accessioned | 2017-03-07T15:32:17Z | |
| dc.date.available | 2017-03-07T15:32:17Z | |
| dc.identifier | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000700005 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/386888 | |
| dc.description | Background: HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a defined entity. However, there are many patients not well characterized with a similar clinical picture who are HTLV-I seronegative. Objective: Clinical and neurophysiological description of patients with HTLV-I seronegative idiopathic paraparesia. Patients and Methods: Seventeen patients (4 women and 13 men aged 24-67 years, average 52.3) were evaluated including clinical assessment, vibratory sensory analysis, quantitative somatosensory thermotest (QST), somatosensory evoked potentials (SSEPs), electromyography (EMG) and motor and sensory nerve conductions. Results: In addition to the spastic paraparesis, 3 (17.6%) patients had pseudobulbar symptoms. Ten (58.8%) patients had a spastic gait but could walk unaided, 6 (35.2%) needed support and 1 patient could not walk. Bladder dysfunction was found in 10 (58.8) patients and sensory symptoms in 7 (41.1%). There was mild distal impairment of vibration and position sense, distal tactile and pinprick hypoesthesia in 4 (23.4%) patients. Tibial SSEPs were abnormal in 11 (64.7%). Nerve conduction studies and EMG were normal. QST showed cold hypoesthesia in 14 (82.4%) patients. Warm sensation and heat pain appeared unimpaired. Conclusions: All sensory abnormalities found were restricted to sensations carried by myelinated (A beta and A delta) channels. Sensory and motor abnormalities are similar to HAM/TSP patients suggesting a common pathogenesis (Rev Méd Chile 2001; 129: 731-41) | |
| dc.format | text/html | |
| dc.language | es | |
| dc.publisher | Sociedad Médica de Santiago | |
| dc.source | Revista médica de Chile v.129 n.7 2001 | |
| dc.subject | Progressive spastic paraparesis | |
| dc.subject | HTLV-I | |
| dc.subject | Quantitative Somatosensory Thermotest | |
| dc.subject | Somatosensory Evoked Potentials | |
| dc.subject | Vibratory Sensory Analysis | |
| dc.title | Paraparesia espástica progresiva idiopática HTLV-I seronegativa: Estudio clínico y neurofisiológico de las manifestaciones sensitivas | |
| dc.type | Artículos de revistas | |
