dc.creatorRocher,Adriana E
dc.creatorBlanco,Ana María
dc.creatorPalaoro,Luis A
dc.date2000-09-01
dc.date.accessioned2017-03-07T15:32:03Z
dc.date.available2017-03-07T15:32:03Z
dc.identifierhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000900002
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/386840
dc.descriptionBackground: AgNOR technique detects, using silver salts, argyrophylic proteins of the nucleolar organizer region (NOR). The number and size of NOR reflect cell activity, proliferation and transformation and may help to differentiate benign from malignant cells. Aim: To assess the value of AgNOR assay to differentiate reactive mesothelial cells from malignant cells in serous effusions. Material and methods: Thirty one fluids obtained from 16 pleural, 14 peritoneal and one pericardial effusion, were studied. The fluids were processed with Giemsa and Papanicolau stains and with the AgNOR technique. The number of AgNOR dots were counted (only when it was possible to distinguish each individual dot) and the mean value per nucleus was calculated for each smear. Results: Mesothelial cells had a mean of 4,88 ± 1,5 dots compared with 13,78 ± 3,88 dots in the malignant cells (p<0,001). Conclusions: AgNOR assay can be useful for the differentiation of benign and malignant cells in serous effusions. (Rev Méd Chile 2000; 128: 963-8)
dc.formattext/html
dc.languagees
dc.publisherSociedad Médica de Santiago
dc.sourceRevista médica de Chile v.128 n.9 2000
dc.subjectCytodiagnosis
dc.subjectCytological techniques
dc.subjectNeoplasm metastasis
dc.subjectSerous membrane
dc.titleUtilidad de la técnica de AgNOR en la interpretación de los derrames de cavidades serosas
dc.typeArtículos de revistas


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