Synthesis and antibacterial activity of cefotaxime metal complexes

dc.creatorAnacona,J.R.
dc.creatorSilva,Gladys Da
dc.date2005-06-01
dc.date.accessioned2017-03-07T15:25:23Z
dc.date.available2017-03-07T15:25:23Z
dc.identifierhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072005000200001
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/384719
dc.descriptionCefotaxime (Hcefotax) interacts with transition metal ions to give [M(cefotax)Cl] complexes (M = Mn(II), Fe(III), Co(II), Ni(II), Cu(II) and Cd(II)) which were characterized by physicochemical and spectroscopic methods and a tetrahedral geometry is suggested for their structure. The IR and the ¹H-NMR spectra of the complexes suggest that the cefotaxime behaves as monoanionic tridentate ligand . The complexes have been screened for antibacterial activity against several bacteria, and the results are compared with the activity of cefotaxime
dc.formattext/html
dc.languageen
dc.publisherSociedad Chilena de Química
dc.sourceJournal of the Chilean Chemical Society v.50 n.2 2005
dc.titleSynthesis and antibacterial activity of cefotaxime metal complexes
dc.typeArtículos de revistas


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