AZORELLANE DITERPENOIDS FROM LARETIA ACAULIS, AND ITS TOXOPLASMACIDAL ACTIVITY

dc.creatorLOYOLA,LUIS A.
dc.creatorBORQUEZ,JORGE
dc.creatorMORALES,GLAUCO
dc.creatorARAYA,JORGE
dc.creatorGONZALEZ,JORGE
dc.creatorNEIRA,IVAN
dc.creatorSAGUA,HERNAN
dc.creatorSAN-MARTÍN,AURELIO
dc.date2001-03-01
dc.date.accessioned2017-03-07T15:09:15Z
dc.date.available2017-03-07T15:09:15Z
dc.identifierhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0366-16442001000100003
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/378981
dc.descriptionIn addition to azorellanol a new diterpenoid 7-deacetylazorellanol, has been isolated from the aerial parts of Laretia acaulis (Cav.) Gill et Hook (Umbelliferae). Its structure was based on spectroscopic comparison with azorellanol and chemical grounds. Azorellanol and 7-deacetylazorellanol showed marked inhibitor activity against trophozoites of protozoan parasite Toxoplasma gondii. The 50 % inhibitory dose for azorellanol was calculated in 54 muM and for 7-deacetylazorellanol was 42 mM.
dc.formattext/html
dc.languageen
dc.publisherSociedad Chilena de Química
dc.sourceBoletín de la Sociedad Chilena de Química v.46 n.1 2001
dc.subjectLaretia acaulis
dc.subjectditerpenoids
dc.subjectazorellanol
dc.subject7-deacetylazorellanol
dc.subjectToxoplasma gondii
dc.titleAZORELLANE DITERPENOIDS FROM LARETIA ACAULIS, AND ITS TOXOPLASMACIDAL ACTIVITY
dc.typeArtículos de revistas


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