Total Synthesis of Rutaecarpine and Analogues by Tandem Azido Reductive Cyclization Assisted by Microwave Irradiation

dc.creatorKamal, A.
dc.creatorReddy, M.K.
dc.creatorReddy, T.S.
dc.creatorSantos, L.S.
dc.creatorShankaraiah, N.
dc.date2012-12-03T22:43:05Z
dc.date2012-12-03T22:43:05Z
dc.date2011
dc.date.accessioned2017-03-07T14:58:48Z
dc.date.available2017-03-07T14:58:48Z
dc.identifierSYNLETT Issue: 1 Pages: 61-64 DOI: 10.1055/s-0030-1259095
dc.identifier0936-5214
dc.identifierhttp://dspace.utalca.cl/handle/1950/9134
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/375907
dc.descriptionSantos, LS (Silva Santos, Leonardo). Univ Talca, Lab Asymmetr Synth, Chem Inst Nat Resources, Talca, Chile.
dc.descriptionThe total synthesis of rutaecarpine and several analogues has been developed by using an azido reductive cyclization process starting from substituted azido benzoic acids. The intramolecular azido reductive cyclization step was performed with triphenylphosphine or Ni2B in HCl-MeOH (1 M) using microwave irradiation. This synthetic route is amenable for the generation of a library of quinazolinone compounds.
dc.languageen
dc.publisherGEORG THIEME VERLAG
dc.subjectquinazolinones
dc.subjectbeta-carbolines
dc.subjectazido-reductive cyclization
dc.subjectNi2B
dc.subjectmicrowave irradiation
dc.titleTotal Synthesis of Rutaecarpine and Analogues by Tandem Azido Reductive Cyclization Assisted by Microwave Irradiation
dc.typeArtículos de revistas


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