| dc.creator | Milagre, C.D.F. | |
| dc.creator | Milagre, H.M.S. | |
| dc.creator | Santos, L.S. | |
| dc.creator | Lopes, M.L.A. | |
| dc.creator | Moran, P.J.S. | |
| dc.creator | Eberlin, M.N. | |
| dc.creator | Rodrigues, J.A.R. | |
| dc.date | 2008-04-18T21:48:49Z | |
| dc.date | 2008-04-18T21:48:49Z | |
| dc.date | 2007 | |
| dc.date.accessioned | 2017-03-07T14:47:09Z | |
| dc.date.available | 2017-03-07T14:47:09Z | |
| dc.identifier | Journal of Mass Spectrometry 42 (10):1287-1293 | |
| dc.identifier | 1076-5174 | |
| dc.identifier | http://dspace.utalca.cl/handle/1950/4875 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/372721 | |
| dc.description | Leonardo S. Santos. Instituto de Química de Recursos Naturales, Universidad de Talca, Talca, Chile. | |
| dc.description | Reactions promoting direct Mannich-type -methylenation of , and -ketoesters have been monitored via electrospray ionization mass and tandem mass spectrometric experiments. Key intermediates of the catalytical cycle of this synthetically useful reaction have been intercepted and characterized. The mechanistic information provided by electrospray ionization mass spectrometry/mass spectrometry (ESI-MS/MS) guided the optimization of reaction conditions, allowing -methyleneketoesters to be prepared in high yields (80-95%) and in high-enough purity for immediate further manipulation. Copyright © 2007 John Wiley & Sons, Ltd. | |
| dc.format | 2977 bytes | |
| dc.format | text/html | |
| dc.language | en | |
| dc.publisher | Wiley Interscience | |
| dc.subject | ketoesters;-methylenation; electrospray ionization mass spectrometry; reaction mechanisms | |
| dc.title | Probing the mechanism of direct Mannich-type alpha-methylenation of ketoesters via electrospray ionization mass spectrometry | |
| dc.type | Artículos de revistas | |
