dc.creatorOrtiz, Johanna
dc.creatorNewman, Steven Anthony
dc.creatorArévalo, Sinay
dc.creatorRestrepo, Héctor Fabio
dc.date.accessioned2020-06-11T13:22:19Z
dc.date.accessioned2022-09-22T15:08:55Z
dc.date.available2020-06-11T13:22:19Z
dc.date.available2022-09-22T15:08:55Z
dc.date.created2020-06-11T13:22:19Z
dc.identifier0120-2448
dc.identifierhttps://repository.urosario.edu.co/handle/10336/25091
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/3445495
dc.description.abstractPurpose: Parkinson disease (PD) is a degenerative disorder. The clinical symptoms of this disease are resting tremor, rigidity and bradykinesia. The purpose of this literature review is to determine the utility of TRODAT -1 in the diagnosis of PD. A search covered PUBMED, COCHRANE, MEDLINE, LILACS and SCIELO databases, between January 1998 and January 2008. Study selection: twenty six articles were obtained with their respective abstracts. After the first review, ten of them were chosen and only six of them met the inclusion criteria. Four articles were classified as grade evidence (+) and two as grade evidence (-) according to NICE guides. All the articles reviewed report significantly decreased striatal uptake of TRODAT-1 in early PD patients, suggesting that this is a useful, safe, and inexpensive tool in the diagnosis of early PD. It was not possible to perform a meta-analysis with the chosen articles because only three of them reported sensitivity and specificity, and each of these used different criteria for their semi-quantitative analyses. This variability makes comparison of the semiquantitative uptake criteria impossible. Conclusions: establishment of a universal technique for quantitation of TRODAT-1 uptake is necessary in order to make meta-analysis viable and allow comparison of the usefulness of this agent among large numbers of patients and multiple populations (Acta Med Colomb 2010; 35: 119-125).
dc.languagespa
dc.publisherAsociacion Colombiana de Medicina Interna
dc.relationActa Medica Colombiana, ISSN:0120-2448, Vol.35, No.3 (2010); pp. 119-125
dc.relation125
dc.relationNo. 3
dc.relation119
dc.relationActa Medica Colombiana
dc.relationVol. 35
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsAbierto (Texto Completo)
dc.sourceinstname:Universidad del Rosario
dc.sourcereponame:Repositorio Institucional EdocUR
dc.subjectenfermedad de Parkinson
dc.subjectenfermedad de Parkinson idiopática
dc.subjectenfermedad de Parkinson con cuerpos de Lewy
dc.subjectparálisis agitante
dc.subject99m Tc TRODAT-1
dc.subjectSPECT
dc.subjecttomografía computarizada de emisión de fotón simple
dc.subjectTC de emisión de fotón único
dc.titleUtilidad del (99m) Tc TRODAT-1 en el diagnóstico de la enfermedad de Parkinson
dc.typearticle


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