Descripción de factores sociodemográficos y clínicos en pacientes con MINOCA y pacientes con enfermedad coronaria obstructiva

Abstract

Introduction: Acute myocardial infarction in patients with non-obstructive coronary disease (less than 50% of the lumen diameter of the vessel), known as MINOCA (Myocardial Infarction with Non-Obstructive Coronary Arteries), is a recently described clinical entity, and poorly characterized both globally and locally. Its sociodemographic and clinical differences with obstructive coronary disease are not clarified in the local context. The objective of this study is to describe sociodemographic and clinical factors in patients with MINOCA and patients with obstructive coronary disease. Methodology: Analytical observational cross-sectional study. Results: 641 patients were included, 117 with MINOCA. The compound primary outcome studied (Death of any origin, Cardiogenic shock, Killip Class> I, LVEF <30%, Glomerular filtration rate <60 thousand / min / 1.73 m2 or nights of hospital stay> 7) was presented in 37.6% of patients with MINOCA vs 54.4% in the group of obstructive coronary disease. Differences are observed between patients with obstructive coronary disease vs MINOCA in the prevalence of smoking history (23.9% vs. 13.7%), diabetes (25.6% vs. 13.7%), previous surgical myocardial revascularization (9.4% vs. 0.9%), presentation as STEMI (43.5% vs 17.9%), presentation of subepicardial injury (39.7% vs 16.2%) and median ejection fraction (45 vs 53). Conclusions: The factors that have been associated in the literature with worse outcomes in acute coronary syndrome occurred more frequently in the group of obstructive vs. non-obstructive coronary disease.