Caracterización de un programa de optimización de antimicrobianos en la prescripción de Ampicilina/sulbactam en un hospital pediátrico

dc.contributorGutiérrez Tobar, Iván Felipe
dc.contributorLópez-Cabra, Claudia-Alejandra
dc.creatorRiaño Galvis, Oscar Eduardo
dc.creatorCerinza Villanueva, Diana Paola
dc.date.accessioned2021-02-16T23:59:01Z
dc.date.available2021-02-16T23:59:01Z
dc.date.created2021-02-16T23:59:01Z
dc.identifierhttps://doi.org/10.48713/10336_30924
dc.identifierhttps://repository.urosario.edu.co/handle/10336/30924
dc.description.abstractIntroduction: Approximately 50% of antibiotic prescriptions are inappropriate, promoting the appearance of bacterial resistance, a public health problem in the world. Antimicrobial optimization programs (PROA) promote the rational use of antibiotics. Ampicillin / sulbactam is an antibiotic frequently used in pediatrics; however, studies that describe the impact of a PROA on narrow-spectrum antibiotics are unknown. Objective: To describe the characteristics of the Ampicillin / sulbactam prescription before and after the execution of a PROA in a pediatric hospital. Methodology: An observational descriptive study was carried out describing the characteristics of the Ampicillin / sulbactam prescription before and immediately after the execution of a PROA in children under 18 years of age by a third-level pediatric hospital in Bogotá, Colombia, making some comparisons between the periods. The clinical variables, antibiotic consumption measured in DOT and hospital costs were evaluated. The data were analyzed using SPSS. Results: 307 patients were included, divided into two groups, before (N = 120) and after the execution of the PROA (N = 187) by the institution. It was observed after the application of PROA that the days of therapy (DOT) of Ampicillin / sulbactam decreased by 68.4%, 425 to 132 per 1000 patient-days (p = 0.002); as well as, costs by 64.6%, from COP $ 93,500,000 to COP $ 33,087,500, derived from the decrease in direct consumption of vials per month. Conclusions: It was observed that the antibiotic consumption and the hospital costs of Ampicillin / sulbactam showed a decrease after the execution of the PROA.
dc.languagespa
dc.publisherUniversidad del Rosario
dc.publisherEscuela de Medicina y Ciencias de la Salud
dc.publisherEspecialización en Pediatría
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsAbierto (Texto Completo)
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dc.rightshttp://creativecommons.org/licenses/by-nd/2.5/co/
dc.rightsAtribución-SinDerivadas 2.5 Colombia
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dc.sourceinstname:Universidad del Rosario
dc.sourcereponame:Repositorio Institucional EdocUR
dc.subjectPrescripción de antibiótico
dc.subjectResistencia antibiótica
dc.subjectPrograma de control de infecciones hospitalarias
dc.subjectUso racional de antibióticos
dc.subjectAhorro para la salud
dc.titleCaracterización de un programa de optimización de antimicrobianos en la prescripción de Ampicilina/sulbactam en un hospital pediátrico
dc.typebachelorThesis


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