article
Pulmonary Embolism Secondary to Inappropriate use of Oral Contraceptive Therapy
Registro en:
ISSN 1561-2988
ISSN: 2329-6887
Autor
Calderón-Ospina, SCarlos
Dominguez-Dominguez, Camilo Alberto
Nava-Mesa, Mauricio O.
Institución
Resumen
Forty-one year old female admitted to the hospital due to a clinical presentation suggestive of pulmonary thromboembolism which was confirmed by CT angiography. There was no history of prior thromboembolic events, smoking, venous stasis or vascular lesion (negative lupus anticoagulant and anticardiolipins). The only documented hypercoagulability factor found was the use of an oral contraceptive containing drospirenone and ethinylestradiol for the last year. The patient was anticoagulated with enoxaparin recovered without sequelae, and is currently receiving outpatient treatment with warfarin. It is well known that the use of combined oral contraceptives is contraindicated in patients over the age of 35, in large part due to the increased risk of thromboembolic events associated with an increased hepatic synthesis of some coagulation factors. Therefore, this represents a case of a serious adverse reaction, potentially fatal, and completely preventable.