| dc.creator | Sobarzo, C | |
| dc.creator | Bustos-Obregon, E | |
| dc.date | 2000 | |
| dc.date | 2021-04-30T16:35:20Z | |
| dc.date | 2021-04-30T16:35:20Z | |
| dc.date.accessioned | 2021-06-14T22:07:47Z | |
| dc.date.available | 2021-06-14T22:07:47Z | |
| dc.identifier | ASIAN JOURNAL OF ANDROLOGY,Vol.2,147-150,2000 | |
| dc.identifier | http://repositoriodigital.uct.cl/handle/10925/3120 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/3301181 | |
| dc.description | Aim: To investigate the toxic effect of a single injection of the organophosphorous agropesticide, parathion, on spermatogenesis in immature male mice. Methods: Seven-day old mice received a single injection of parathion intraperitoneally at a dose of 1/3 LD50. The epididymal sperm count, sperm morphology and chromatin thermal stability were analyzed 28 and 50 days after injection. Results: Sperm counts were decreased and teratozoospermia and thermal denaturation of DNA increased after parathion injection. Sperm parameters were changed to a greater extent in younger animals, denoting a higher lability of spermatogenic process at its beginning. The damages could recover a long time after parathion administration. Conclusion: Organophosphorous agropesticides are testicular toxicants, eliciting reversible cytotoxic and cytogenetic alterations in germ cells. | |
| dc.language | en | |
| dc.publisher | WOLTERS KLUWER MEDKNOW PUBLICATIONS | |
| dc.source | ASIAN JOURNAL OF ANDROLOGY | |
| dc.subject | epididymis | |
| dc.subject | spermatozoa | |
| dc.subject | organophosphorous compounds | |
| dc.subject | agropesticides | |
| dc.subject | spermatogenesis | |
| dc.title | Sperm quality in mice acutely treated with parathion | |
| dc.type | Article | |
