dc.creatorBaroni, E
dc.creatorAhumada, F
dc.creatorLuders, C
dc.creatorSaavedra, I
dc.creatorZambucetti, R
dc.date2000
dc.date2021-04-30T17:04:08Z
dc.date2021-04-30T17:04:08Z
dc.date.accessioned2021-06-14T22:01:29Z
dc.date.available2021-06-14T22:01:29Z
dc.identifierARCHIVOS DE MEDICINA VETERINARIA,Vol.32,193-200,2000
dc.identifierhttp://repositoriodigital.uct.cl/handle/10925/3827
dc.identifier10.4067/S0301-732X2000000200006
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/3298896
dc.descriptionPharmacokinetic variables of propofol were studied in 8 foals. Plasma levels of propofol at different time after a single intravenous dose of 2.4 mg/kg bw, were determined by HPLC. An open two compartments model was used to evaluate plasma levels of propofol and values of t(1/2)alpha, t(1/2)beta Vd(c), Vd(ss), Vd beta, Cl-total y MRT were obtained. Propofol pharmacokinetic disposition showed a rapid distribution and removal from organic tissues, and the reported pharmacokinetic variables contribute to determine the appropriate dose to be given.
dc.languagees
dc.publisherUNIV AUSTRAL CHILE. FAC CIENCIAS VETERINARIAS
dc.sourceARCHIVOS DE MEDICINA VETERINARIA
dc.subjectpharmacokinetic
dc.subjectpropofol
dc.subjectfoals
dc.titlePharmacokinetics of propofol in 10 to 15 days old foals
dc.typeReview


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