artículo
2-Methoxyestradiol inhibits progesterone-dependent tissue factor expression and activity in breast cancer cells
Fecha
2010Registro en:
10.1007/s12672-010-0019-5
Autor
Quezada, M.
Diaz, J.
Henriquez, S.
Bravo Castillo, María Loreto
Aranda, E.
Oliva, B.
Villalón, Manuel J.
Kato Cardemil, Sumie Rode
Cuello F., Mauricio
Brosens, J. J.
Lange, C. A.
Owen, Gareth Ivor
Institución
Resumen
2-Methoxyestradiol (2ME) is an endogenous metabolite of 17β-estradiol with antiangiogenic and antitumor properties, although its mechanisms of action remain unclear. Progestins in hormone replacement therapy increase the risk of breast cancer. Progesteron