M2 macrophages do not fly into a “RAGE”

dc.creatorRojas, Armando
dc.creatorAraya, Paulina
dc.creatorAñazco-Oyarzún, Carolina
dc.date2017-09-28T15:58:05Z
dc.date2017-09-28T15:58:05Z
dc.date2017
dc.date.accessioned2019-11-20T15:07:31Z
dc.date.available2019-11-20T15:07:31Z
dc.identifierhttp://repositorio.ucm.cl:8080/handle/ucm/243
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/3031983
dc.descriptionTumor-associated macrophages (TAMs) are key elements in orchestrating host responses inside tumor stroma. This population may undergo a polarized activation process, thus rendering a heterogeneous spectrum of phenotypes, where the classically activated type 1 macrophages (M1) and the alternative activated type 2 macrophages (M2) represent two extreme phenotypes. In this commentary, based on very recent research findings, we intend to highlight how complex could be the crosstalk among all components of tumor stroma, where the coexistence of non-natural partners may even skew the canonical responses that we can expect.
dc.languageen
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Chile
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.sourceInflammation Research, 66(1), 13-15
dc.subjectReceptor of advanced glycation end products
dc.subjectTumor microenvironment
dc.subjectMacrophage polarization
dc.subjectHMGB1
dc.subjectM2 macrophages
dc.titleM2 macrophages do not fly into a “RAGE”
dc.typeArtículos de revistas


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