Artículo de revista
Antiplatelet therapy in patients undergoing oral surgery: A systematic review and meta-analysis
Fecha
2019Registro en:
Medicina Oral Patología Oral y Cirugía Bucal, Volumen 24, Issue 1, 2019, Pages e103-e113
16986946
16984447
10.4317/medoral.22708
Autor
Villanueva Maffei, Julio
Salazar, Josefina
Alarcón Arratia, Ana
Araya Cabello, Ignacio
Yanine Montaner, Nicolás
Domancic Alucema, Stefan
Carrasco Labra, Alonso
Institución
Resumen
Background: The number of patients under antiplatelet therapy (APT) continues to raise as current recommendations
foster this practice. Although some recommendations to manage this treatment during oral surgery procedures
exist, these have methodological shortcomings that preclude them from being conclusive.
Material and Methods: A systematic review and meta-analysis of the best current evidence was carried out; The
Cochrane Library, EMBASE and MEDLINE databases were searched for Randomized Controlled Trials (RCT)
concerning patients undergoing oral surgery with APT, other relevant sources were searched manually.
Results: 5 RCTs met the Inclusion criteria. No clear tendency was observed (RR= 0.97 CI 95%: 0,41–2,34; p=0,09;
I2= 51%), moreover, they weren’t clinically significant.
Conclusions: According to these findings and as bleeding is a manageable complication it seems unreasonable to
undermine the APT, putting the patient in danger of a thrombotic event and its high inherent morbidity, which isn’t
comparable in severity and manageability to the former.”