Comparison of Pheochromocytoma-Specific Morbidity and Mortality among Adults with Bilateral Pheochromocytomas Undergoing Total Adrenalectomy vs Cortical-Sparing Adrenalectomy

dc.creatorNeumann, Hartmut P.H.
dc.creatorTsoy, Uliana
dc.creatorBancos, Irina
dc.creatorAmodru, Vincent
dc.creatorWalz, Martin K.
dc.creatorTirosh, Amit
dc.creatorKaur, Ravinder Jeet
dc.creatorMcKenzie, Travis
dc.creatorQi, Xiaoping
dc.creatorBandgar, Tushar
dc.creatorPetrov, Roman
dc.creatorYukina, Marina Y.
dc.creatorRoslyakova, Anna
dc.creatorVan Der Horst-Schrivers, Anouk N.A.
dc.creatorBerends, A
dc.date.accessioned2019-10-11T17:27:18Z
dc.date.available2019-10-11T17:27:18Z
dc.date.created2019-10-11T17:27:18Z
dc.date.issued2019
dc.identifier25743805
dc.identifier10.1001/jamanetworkopen.2019.8898
dc.identifierhttps://repositorio.uchile.cl/handle/2250/171164
dc.description.abstract© 2019 American Medical Association. All rights reserved.Importance: Large studies investigating long-term outcomes of patients with bilateral pheochromocytomas treated with either total or cortical-sparing adrenalectomies are needed to inform clinical management. Objective: To determine the association of total vs cortical-sparing adrenalectomy with pheochromocytoma-specific mortality, the burden of primary adrenal insufficiency after bilateral adrenalectomy, and the risk of pheochromocytoma recurrence. Design, Setting, and Participants: This cohort study used data from a multicenter consortium-based registry for 625 patients treated for bilateral pheochromocytomas between 1950 and 2018. Data were analyzed from September 1, 2018, to June 1, 2019. Exposures: Total or cortical-sparing adrenalectomy. Main Outcomes and Measures: Primary adrenal insufficiency, recurrent pheochromocytoma, and mortality. Results: Of 625 patients (300 [48%] female) with a median (interquartile range [IQR]) ag
dc.languageen
dc.publisherAmerican Medical Association
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.sourceJAMA Network Open
dc.subjectMedicine (all)
dc.titleComparison of Pheochromocytoma-Specific Morbidity and Mortality among Adults with Bilateral Pheochromocytomas Undergoing Total Adrenalectomy vs Cortical-Sparing Adrenalectomy
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución