Artículo de revista
Early laparoscopic cholecystectomy reduces hospital stay in mild gallstone pancreatitis. A randomized controlled trial
Fecha
2020Registro en:
14772574
1365182X
10.1016/j.hpb.2019.05.013
Autor
Riquelme, Francisco
Marinkovic, Boris
Salazar, Marco
Martínez, Waldo
Catan, Felipe
Uribe-Echevarría, Sebastián
Puelma, Felipe
Muñoz, Jorge
Canals, Andrea
Astudillo, Cristian
Uribe, Mario
Institución
Resumen
© 2019 International Hepato-Pancreato-Biliary Association Inc.Background: Two strategies for same-admission cholecystectomy in mild gallstone pancreatitis (MGP) exist: early surgery (within 48–72 h from admission) and delayed surgery until resolution of symptoms and normalization of pancreatic tests. Methods: This was a single-center, open-label RCT. Patients with MGP according to revised Atlanta classification-2012 and SIRS criteria were randomly assigned to early laparoscopic cholecystectomy (E-LC) within 72 h from admission or delayed laparoscopic cholecystectomy (D-LC). Laparoscopic-endoscopic rendezvous was performed when common bile duct stones were found at systematic intraoperative cholangiography. The primary outcome was length of stay (LOS), and the secondary outcomes were complications at 90 days, need for ERCP/choledocolithiasis, conversion, and re-admission. One year of follow-up was carried-on. Results: At interim analysis, 52 patients were randomized (26 E-LC, 26 D-LC).