dc.creatorAranda, Alfredo
dc.creatorValencia, Alvaro
dc.date.accessioned2019-05-31T15:20:02Z
dc.date.available2019-05-31T15:20:02Z
dc.date.created2019-05-31T15:20:02Z
dc.date.issued2018
dc.identifierJournal of Mechanics in Medicine and Biology, Volumen 18, Issue 5, 2018, Pages 1850055-1 - 1850055-16
dc.identifier02195194
dc.identifier10.1142/S0219519418500550
dc.identifierhttps://repositorio.uchile.cl/handle/2250/169431
dc.description.abstractCFD simulations were performed for 60 human cerebral aneurysms (30 previously ruptured and 30 previously unruptured) to study the behavior of the time-averaged wall shear stress (TAWSS) with respect to the aspect ratio (AR), implementing a set of low, normal, and highpressure differences between the inlet and the outlets of each artery. It is well known that there exists a direct relationship between TAWSS and the rupture. In this investigation, we presented an important result because the condition of the pressure among the branches and the AR may be measured in any patient, then a slope may be associated, and finally a TAWSS may be estimated. We found that when the pressure difference increased, the absolute slopes between TAWSS and AR increased as well. Also, the magnitude of the slope in the previously unruptured aneurysms was 4.7 times the slope in the previously ruptured aneurysms. On the other hand, TAWSS was higher in the previously unruptured aneurysm than previously ruptured aneurysms due to the unruptured aneurysms that have a smaller surface area. Furthermore, we analyzed the relationship between TAWSS and other geometric parameters of the aneurysm, such as bottleneck and non-sphericity index; however, no correlation was found for either cases.
dc.languageen
dc.publisherWorld Scientific Publishing Co. Pte Ltd
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.sourceJournal of Mechanics in Medicine and Biology
dc.subjectaspect ratio
dc.subjectcerebral aneurysm simulations
dc.subjectCFD
dc.subjectpressure difference
dc.subjectwall shear stress
dc.titleStudy on the relationship between wall shear stress and aspect ratio of cerebral aneurysms with different pressure differences using cfd simulations
dc.typeArtículo de revista


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