dc.creator | Cruz lopez, María del Carmen | |
dc.date.accessioned | 2012-11-25T22:49:02Z | |
dc.date.available | 2012-11-25T22:49:02Z | |
dc.date.created | 2012-11-25T22:49:02Z | |
dc.date.issued | 2012-11-25 | |
dc.identifier | http://www.repositoriodigital.ipn.mx/handle/123456789/8532 | |
dc.description.abstract | A new approach is described for the synthesis of substituted
indoles 5, through an intramolecular and regioselective
Friedel–Crafts cyclization of enaminones 6a–h catalyzed by Lewis
acids. Compounds 6 were prepared from the 2-anilinocarbonyl
compounds 7, by treatment with DMFDMA under thermal or microwave
(MW) irradiation conditions. An alternative and shorter
one-pot two-step synthesis of indoles 5 was achieved starting from
compounds 7 and promoted by MW radiation, including the elusive
2-acetylindoles 5i–m. | |
dc.language | en | |
dc.subject | indoles, | |
dc.subject | enaminones | |
dc.title | Regioselective and Versatile Synthesis of Indoles via Intramolecular Friedel–Crafts Heteroannulation of Enaminones | |
dc.type | Article | |