dc.contributor | Flores, Alex Fabiani Claro | |
dc.contributor | http://lattes.cnpq.br/1159954352174167 | |
dc.contributor | Morel, Ademir Farias | |
dc.contributor | http://lattes.cnpq.br/3554994385525333 | |
dc.contributor | Siqueira, Geonir Machado | |
dc.contributor | http://lattes.cnpq.br/3245577879591660 | |
dc.contributor | Mostardeiro, Marco Aurelio | |
dc.contributor | http://lattes.cnpq.br/6195396264565980 | |
dc.contributor | Beck, Paulo Henrique | |
dc.contributor | http://lattes.cnpq.br/4175014494565472 | |
dc.creator | Frigo, Leandro Marcon | |
dc.date.accessioned | 2017-05-18 | |
dc.date.available | 2017-05-18 | |
dc.date.created | 2017-05-18 | |
dc.date.issued | 2013-09-30 | |
dc.identifier | FRIGO, Leandro Marcon. Attainment of new heterocycles derived from levulinic acid. 2013. 230 f. Tese (Doutorado em Química) - Universidade Federal de Santa Maria, Santa Maria, 2013. | |
dc.identifier | http://repositorio.ufsm.br/handle/1/4263 | |
dc.description.abstract | This study describes the attainment of twenty three (23) bis-heterocycles derived from the Levulinic Acid: Bis-Pyrazoles (6a-k) by the reaction of cyclecondensation between the 3-(5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-3-il)propanohidrazidamand a series of replaced β-alcoxiviniltrifluorometilcetonas. 1,3,4-oxadiazole 2-5-disubstituted (8-11) by reactions like [4 + 1] [OCNN+C], through the reactions of cyclecondensation between the 3-(5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-3-yl)propanohidrazida with different orthoesters as well as with carbon disulfide. It was also produced hydrazides (16c-d, g-h e 17c-d, g-h) derived of synthesized pyrimidines, to be used as precursorsn in the synthesis of bis-heterocycles, derivatizated of the reaction of those with some β- Ketones alcoxiviniltrifluormetil. The bis-heterocycles were obtained by the ordinary methodology, with efficiency between 61-97%.It was also gotten other original compounds (3i-k, 5), used as precursors in this study. The structure of these synthesized compounds were confirmed by the data of RMN 1H, 13C, besides the data of mass spectrometry. | |
dc.publisher | Universidade Federal de Santa Maria | |
dc.publisher | BR | |
dc.publisher | Química | |
dc.publisher | UFSM | |
dc.publisher | Programa de Pós-Graduação em Química | |
dc.rights | Acesso Aberto | |
dc.subject | Oxadiazóis | |
dc.subject | Pirimidinas | |
dc.subject | Pirazóis | |
dc.subject | Bis-heterociclos | |
dc.subject | Oxadiazole | |
dc.subject | Pyrimidines | |
dc.subject | Pyrazoles | |
dc.subject | Bis-heterocycles | |
dc.title | Obtenção de novos heterociclos derivados do ácido levulínico | |
dc.type | Tese | |