dc.contributorFlores, Alex Fabiani Claro
dc.contributorhttp://lattes.cnpq.br/1159954352174167
dc.contributorMorel, Ademir Farias
dc.contributorhttp://lattes.cnpq.br/3554994385525333
dc.contributorSiqueira, Geonir Machado
dc.contributorhttp://lattes.cnpq.br/3245577879591660
dc.contributorMostardeiro, Marco Aurelio
dc.contributorhttp://lattes.cnpq.br/6195396264565980
dc.contributorBeck, Paulo Henrique
dc.contributorhttp://lattes.cnpq.br/4175014494565472
dc.creatorFrigo, Leandro Marcon
dc.date.accessioned2017-05-18
dc.date.available2017-05-18
dc.date.created2017-05-18
dc.date.issued2013-09-30
dc.identifierFRIGO, Leandro Marcon. Attainment of new heterocycles derived from levulinic acid. 2013. 230 f. Tese (Doutorado em Química) - Universidade Federal de Santa Maria, Santa Maria, 2013.
dc.identifierhttp://repositorio.ufsm.br/handle/1/4263
dc.description.abstractThis study describes the attainment of twenty three (23) bis-heterocycles derived from the Levulinic Acid: Bis-Pyrazoles (6a-k) by the reaction of cyclecondensation between the 3-(5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-3-il)propanohidrazidamand a series of replaced β-alcoxiviniltrifluorometilcetonas. 1,3,4-oxadiazole 2-5-disubstituted (8-11) by reactions like [4 + 1] [OCNN+C], through the reactions of cyclecondensation between the 3-(5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-3-yl)propanohidrazida with different orthoesters as well as with carbon disulfide. It was also produced hydrazides (16c-d, g-h e 17c-d, g-h) derived of synthesized pyrimidines, to be used as precursorsn in the synthesis of bis-heterocycles, derivatizated of the reaction of those with some β- Ketones alcoxiviniltrifluormetil. The bis-heterocycles were obtained by the ordinary methodology, with efficiency between 61-97%.It was also gotten other original compounds (3i-k, 5), used as precursors in this study. The structure of these synthesized compounds were confirmed by the data of RMN 1H, 13C, besides the data of mass spectrometry.
dc.publisherUniversidade Federal de Santa Maria
dc.publisherBR
dc.publisherQuímica
dc.publisherUFSM
dc.publisherPrograma de Pós-Graduação em Química
dc.rightsAcesso Aberto
dc.subjectOxadiazóis
dc.subjectPirimidinas
dc.subjectPirazóis
dc.subjectBis-heterociclos
dc.subjectOxadiazole
dc.subjectPyrimidines
dc.subjectPyrazoles
dc.subjectBis-heterocycles
dc.titleObtenção de novos heterociclos derivados do ácido levulínico
dc.typeTese


Este ítem pertenece a la siguiente institución