dc.contributorSoares, Félix Alexandre Antunes
dc.contributorhttp://lattes.cnpq.br/8752453650114092
dc.contributorOliveira, álvaro Reischak de
dc.contributorhttp://lattes.cnpq.br/0641735531407998
dc.contributorPuntel, Gustavo Orione
dc.contributorhttp://lattes.cnpq.br/0319301096075015
dc.contributorRoyes, Luiz Fernando Freire
dc.contributorhttp://lattes.cnpq.br/0543081555633400
dc.creatorFarinha, Juliano Boufleur
dc.date.accessioned2014-10-06
dc.date.available2014-10-06
dc.date.created2014-10-06
dc.date.issued2014-02-19
dc.identifierFARINHA, Juliano Boufleur. Biochemical responses to aerobic training in women with metabolic syndrome. 2014. 72 f. Dissertação (Mestrado em Educação Física) - Universidade Federal de Santa Maria, Santa Maria, 2014.
dc.identifierhttp://repositorio.ufsm.br/handle/1/6712
dc.description.abstractThe sedentary lifestyle and a high fat diet are related with the emergence of metabolic syndrome (MS), which is represented by the cluster of risk factors such abdominal obesity, insulin resistance, dyslipidemia and hypertension. Nowadays, it is well known that both obesity and metabolic syndrome-related cardiovascular diseases are associated with oxidative stress and chronic low-grade inflammation. Considering that regular physical exercise may be considered one of the best non-pharmacological ways to MS prevention and treatment, few studies assessed the effects of moderate aerobic training (AT) alone on oxidative, inflammatory, anthropometric and functional parameters and quality of life in women with MS. Thus, it was investigated the effects of 15 weeks of AT on functional, anthropometric, biochemical profiles and the health-related quality of life (HRQOL) (manuscript 1) and the impact of 12 weeks of AT on body composition and systemic biomarkers of oxidative stress and inflammation in middle-aged women with MS (manuscript 2). Both inverventions comprised three weekly sessions of brisk walking and/or jogging in treadmills, with the training intensity being controlled by heart rate monitors. The 15-week AT decreased waist and hip circumferences, total cholesterol, low-density lipoprotein (LDL), thiobarbituric acid-reactive substances levels (TBARS) and myeloperoxidase and lactate dehydrogenase activities. Furthermore, it was observed an increasing in estimated maximal oxygen uptake and flexibility, albumin and high-density lipoprotein (HDL) levels and higher scores in physical functioning, role-physical, bodily pain, general health and social functioning domains in the HRQOL questionnaire. However, it was not found a simultaneous weight loss (manuscript 1). The 12-week AT provoked reductions in total body fat mass, interleukin-1 beta (IL-1β), interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α), interferom-gamma (INF-γ), advanced oxidation protein products (AOPP) and TBARS levels. In this context, AT resulted in increased total body lean mass, interleukin-10 (IL-10) and total thiol groups content levels, even with the maintenance of nitrite and nitrate (NOx) levels (manuscript 2). Therefore, it was concluded that biochemical, anthropometric and quality of life improved-exercise related parameters are independent of weight loss and that the moderate aerobic training positively modulates inflammation and oxidative stress biomarkers and body composition in middle-aged women with MS.
dc.publisherUniversidade Federal de Santa Maria
dc.publisherBR
dc.publisherEducação Física
dc.publisherUFSM
dc.publisherPrograma de Pós-Graduação em Educação Física
dc.rightsAcesso Aberto
dc.subjectTreinamento aeróbico
dc.subjectSíndrome metabólica
dc.subjectObesidade
dc.subjectInflamação
dc.subjectEstresse oxidativo
dc.subjectAerobic training
dc.subjectMetabolic syndrome
dc.subjectObesity
dc.subjectInflammation
dc.subjectOxidative stress
dc.titleRespostas bioquímicas de mulheres com síndrome metabólica submetidas ao treinamento aeróbico
dc.typeDissertação


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