Trabalho de Conclusão de Curso de Especialização
Tumor maligno de bainha de nervo periférico em um felino - relato de caso
Autor
Cecco, Bianca Santana de
Institución
Resumen
The malignant peripheral nerve sheath tumor, or malignant Schwannoma is an
uncommon tumor in felines, derived from the Schwann cell with high cellular atypia
that infiltrates to the adjacent tissues. The most usual location for this tumor is the skin
or the subcutaneous, where are observed poorly defined masses that are well adhered
to the soft adjacent tissues. Cytology is a useful tool for characterizing a spindle cell
tumor with various criteria of malignancy, helping the physician to choose the
appropriate treatment. For this kind of tumors is required wide surgical excision.
Histopathological examination is required for a definitive diagnosis, and in most cases
is necessary some immunohistochemical techniques, such as vimentin. This paper
describes a case of malignant peripheral nerve sheath tumor in a feline diagnosed by
fine needle aspiration cytology of the tumor, followed by surgical excision of the tumor,
histopathological analysis and immunohistochemistry. The morphologic diagnosis of
mesenchymal neoplasm confirms the suspicion raised by cytology and together were
performed the immunohistochemical panel of vimentin, GFAP, Von Willebrand factor
and cytokeratin. The only marker that showed positive result was vimentin, confirming
the origin of the tumor of mesenchymal cells. The animal showed no local recurrence
or metastases. It is concluded that with the convenience and rapidity of diagnosis by
aspiration cytology was possible to perform surgical excision and effective therapy for
the removal of neoplastic cells, without the animal have to pass by prior anesthesia,
thereby reducing the risk of both anesthetic and surgical complications.